I currently have four computers in my computer room. Two run Lysistrata, one laptop runs Spartacus, and one runs Win XP.
I use the antiX computers about 90% of the time. One is used mainly for testing, the other the bulk of the day to day, and the laptop keeps my financial stuff and other data I want to keep. I also keep this data on a USB disk that makes the rounds.
I have so many computers because I have a reputation of being a computer geek among my circle of friends and family. There's a surprise. Because of this reputation, I get donations of older computer systems that have died, or have been eclipsed by the new technology. I salvage the good parts, create a usable computer, and give it to someone needy.
antiX fits this niche perfectly and the next few computers I give away will have antiX. A few caveats will apply, as well as some antix "basic training". Building the computer has always been the easiest part. I spent way more time with education and support . I actually think this time will shrink with antiX because of its stability.
I use Win XP for the following tasks/applications:
--Terrain Navigator Pro...an excellent topographic map software. I use this for my profession as well as personal. I work as a patrol sergeant for a sheriff's office in a county covering about 8,500 square miles (5.5 million acres). Most of the county is backcountry/wilderness with three large designated wilderness areas. I need an accurate map database for searching for lost persons, responding to emergencies, etc. I also spend considerable time in the backcountry on my personal time with my pack llamas (hence my avatar

). I love to photograph wildlife, fish, and relax miles away from other humans. You may see some of those photographs in the future as wallpaper.
--GPS software...this goes hand in hand with the above. I also am an instructor teaching new deputies and emergency medical personnel fundamental gps technology and use.
--Picasa...for my photographs. I have used Picasa under wine in Mepis 6.5 with reasonable results. I love Picasa because I can do anything I need to do from it. Print photos, upload to web album, email, etc.
--Quicken...although I am transitioning to Moneydance which I have running on my Spartacus laptop.
--Photoshop...although again making the transition to Gimp. Most of my work is done in Gimp at this point but still find some tasks easier in Photoshop.
I plan on experimenting with Picasa and Terrain Navigator Pro under wine in antiX in the near future. I would appreciate any comments or suggestions that might help in that regard. Sorry this got so long...hope it helps.