enable the stable (squeeze) or the unstable (sid) repos in /etc/apt/sources.list.
open run and type
gksu leafpad /etc/apt/sources.list
then remove the # from the beginning of the either of the lines.
deb http://ftp.de.debian.org/debian/ stable main contrib non-free
deb http://ftp.de.debian.org/debian/ unstable main contrib non-free
save the file and as root in a terminal use the commands:
apt-get install wine
(the su command is for becoming root.)
then disable the stable or the unstable repos in /etc/apt/sources.list.
if you can't manage in terminal, open synaptic in antix control center > system > manage packages. go to settings>repositories> and enable the stable or unstable repo. after that hit the reload button and search for wine, mark for install the package wine and hit apply. after you are finished disable the stable/unstable repos in the settings area and you are done.